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Published on: October 24, 2020
Azygos reflux: a CT sign of cardiac tamponade
S R Harries1, B M Fox, C A Roobottom
1Department of Radiology, Derriford Hospital, Plymouth, Devon, UK.
Insights
Dynamic contrast-enhanced computed tomography (CT) revealed contrast reflux into the azygos vein in patients with pericardial effusion. This finding suggests cardiac tamponade, a serious condition impacting hemodynamics.
Area of Science:
- Radiology
- Cardiology
- Medical Imaging
Background:
- Pericardial effusions can be challenging to diagnose clinically.
- Dynamic contrast-enhanced computed tomography (CT) is a key imaging modality for thoracic assessment.
Observation:
- Three patients presented with pericardial effusions and contrast reflux into the azygos vein during thoracic CT.
- This specific CT finding was not observed in 30 control scans using a similar protocol.
Findings:
- Azygos vein contrast reflux in the presence of pericardial effusion is a CT sign suggestive of cardiac tamponade.
- Clinical diagnosis of cardiac tamponade was not initially made in these cases.
- Diagnosis was confirmed via echocardiography or post-mortem examination.
Implications:
- Azygos vein contrast reflux indicates significant hemodynamic compromise.
- This CT finding can aid in the early diagnosis of cardiac tamponade.
- Prompt diagnosis and intervention are crucial for patient outcomes.
Abstract:
Three patients who were investigated with dynamic contrast medium enhanced computed tomography (CT) of the thorax were noted to have pericardial effusions with reflux of contrast medium back along the azygos vein. The diagnosis of cardiac tamponade was not made clinically, but in each case was suggested from the CT findings. Confirmation of the diagnosis was made in all three cases, two patients with echocardiography and one at post mortem. One patient made a rapid recovery following the insertion of a pericardial drain, another made a temporary recovery after pericardiocentesis but the third died. Thirty CT scans performed with similar protocol were reviewed and none of these demonstrated reflux along the azygos vein. The presence of contrast medium refluxing into the azygos vein implies significant haemodynamic disturbance, and in the presence of a pericardial effusion suggests the diagnosis of cardiac tamponade.
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