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[Diagnosis and management of parasitic hypereosinophilia]
1Institut de Parasitologie, Pathologie tropicale, Strasbourg.
Etiology:
Helminth infestation of the digestive tract or organ tissues is a common and curable cause of high eosinophil counts. Parasite infestation should be the number one suspect in patients with hypereosinophilia.
Diagnosis:
Clinical signs and epidemiology are suggestive. If the patient has travelled to the tropics, one should consider both exotic and cosmopolite parasites.
Laboratory Tests:
The causal agent can sometimes be identified by direct examination of tissue samples, depending on the localization. In practice however identification may be a difficult task when the level of infestation is low or the helminth is in a larval stage. The epidemiological situation, clinical features and results of serology tests must all be considered for diagnosis.
Antihelminth Treatment (Test):
Clinical improvement after treatment can be a criteria for positive diagnosis. Normal eosinophil counts followed later by normal serology confirms the diagnosis.