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Tophaceous pseudogout of the mitral valve
M R Moon1, J I Fann, P C Deedwania
1Department of Pathology, Veterans Affairs Health Care System, Palo Alto, California, USA.
The Annals of Thoracic Surgery
|October 13, 1998
Summary
A 61-year-old hemodialysis patient experienced intracardiac masses causing coronary obstruction. Diagnosis revealed tophaceous pseudogout (tumoral calcinosis) of the mitral valve due to calcium pyrophosphate crystal deposition.
Area of Science:
- Cardiology
- Rheumatology
- Nephrology
Background:
- Chronic hemodialysis patients are susceptible to various complications.
- Intracardiac masses can lead to significant cardiovascular events.
Observation:
- A 61-year-old male on chronic hemodialysis presented with multiple left-sided intracardiac masses.
- These masses caused intermittent coronary artery obstruction.
Findings:
- Mitral valve replacement was performed due to the observed masses.
- Histopathological examination revealed massive calcium pyrophosphate crystal deposition in the mitral valve cusps.
- This confirmed the diagnosis of tophaceous pseudogout (tumoral calcinosis) of the mitral valve.
Implications:
- This case highlights an unusual presentation of tumoral calcinosis in a hemodialysis patient.
- It underscores the importance of considering crystal deposition diseases in intracardiac mass etiology.
- Further research into the link between chronic kidney disease, hemodialysis, and tumoral calcinosis is warranted.
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