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[Vascular contrast agents. Definition and potential applications]
1Laboratoire Guerbet, Recherche & Développement, Roissy CDG.
Blood pool agents are characterized by a biodistribution limited to the vascular space after intravenous injection. This is different from uroangiographic agents in CT Scanner or Gd chelates in MRI which are markers for the intra and extravascular space. This unique property is potentially useful for diagnostic applications such as ischemic diseases (myocardial or cerebral perfusion defects), vascular diseases and diagnostic or follow-up of endothelial permeability disorders (diabetic patients, tumors...).
Blood pool agents are characterized by a biodistribution limited to the vascular space after intravenous injection. This is different from uroangiographic agents in CT Scanner or Gd chelates in MRI which are markers for the intra and extravascular space. This unique property is potentially useful for diagnostic applications such as ischemic diseases (myocardial or cerebral perfusion defects), vascular diseases and diagnostic or follow-up of endothelial permeability disorders (diabetic patients, tumors...).