From a DNA helicase to brittle hair

DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway.

Scientific reports·2017

The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells.

The EMBO journal·2001

Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum Group A and Cockayne syndrome Group B DNA repair genes.

Proceedings of the National Academy of Sciences of the United States of America·2001

Sequential assembly of the nucleotide excision repair factors in vivo.

Molecular cell·2001

Differential ultraviolet-B-induced immunomodulation in XPA, XPC, and CSB DNA repair-deficient mice.

The Journal of investigative dermatology·2001

RNA polymerase II elongator holoenzyme is composed of two discrete subcomplexes.

The Journal of biological chemistry·2001

Toward the clinical application of long-read sequencing in repeat-expansion disorders.

Nature genetics·2026

Distinguishing different psychiatric disorders using DDx-PRS.

Nature genetics·2026

Adaptive evolution of polyploid crops.

Nature genetics·2026

Rare variant effect estimation and polygenic risk prediction.

Nature genetics·2026

Spatial analysis of head and neck cancer identifies two ecosystems with distinct modes of epithelial-to-mesenchymal transition.

Nature genetics·2026

PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

Nature genetics·2026

Impact of Concomitant Grade I Degenerative Spondylolisthesis on Clinical and Radiographic Outcomes Following Biportal Endoscopic versus Microscopic Laminectomy for Lumbar Spinal Stenosis: A Post Hoc Analysis of a Multicenter Randomized Clinical Trial.

Global spine journal·2026

HMGB1-targeted anti-inflammatory rBox A gene therapy for viral airway infections and systemic inflammatory disease models.

mBio·2026

Mesenchymal Stem Cell Secretome Mitigates Inflammatory Endothelial Dysfunction.

Shock (Augusta, Ga.)·2026

An Asymmetric Magnetic Hydrogel With Mild Magnetothermal Effect for Safe and Efficient Bone Repair.

Advanced healthcare materials·2026

Dual-gene regulation of NGF overexpression and P75NTR knockdown enhances BMSC osteogenesis by suppressing pyroptosis.

iScience·2026

Automated Standardization of the Shear-wave Elastography Effective Region Using DeepLabV3 Improves Malignancy Assessment in Thyroid Nodules: A Single-institution Multicampus Study.

Academic radiology·2026

Related Experiment Videos

From a DNA helicase to brittle hair

Related Concept Videos

DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway.

The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells.

Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum Group A and Cockayne syndrome Group B DNA repair genes.

Sequential assembly of the nucleotide excision repair factors in vivo.

Differential ultraviolet-B-induced immunomodulation in XPA, XPC, and CSB DNA repair-deficient mice.

RNA polymerase II elongator holoenzyme is composed of two discrete subcomplexes.

Toward the clinical application of long-read sequencing in repeat-expansion disorders.

Distinguishing different psychiatric disorders using DDx-PRS.

Adaptive evolution of polyploid crops.

Rare variant effect estimation and polygenic risk prediction.

Spatial analysis of head and neck cancer identifies two ecosystems with distinct modes of epithelial-to-mesenchymal transition.

PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

Impact of Concomitant Grade I Degenerative Spondylolisthesis on Clinical and Radiographic Outcomes Following Biportal Endoscopic versus Microscopic Laminectomy for Lumbar Spinal Stenosis: A Post Hoc Analysis of a Multicenter Randomized Clinical Trial.

HMGB1-targeted anti-inflammatory rBox A gene therapy for viral airway infections and systemic inflammatory disease models.

Mesenchymal Stem Cell Secretome Mitigates Inflammatory Endothelial Dysfunction.

An Asymmetric Magnetic Hydrogel With Mild Magnetothermal Effect for Safe and Efficient Bone Repair.

Dual-gene regulation of NGF overexpression and P75NTR knockdown enhances BMSC osteogenesis by suppressing pyroptosis.

Automated Standardization of the Shear-wave Elastography Effective Region Using DeepLabV3 Improves Malignancy Assessment in Thyroid Nodules: A Single-institution Multicampus Study.

Related Experiment Videos

From a DNA helicase to brittle hair

Related Concept Videos

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