Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vitamin E and atherosclerosis

A C Chan1

  • 1Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada K1H 8M5.

The Journal of Nutrition
|October 15, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A distinctive epigenetic ageing profile in human granulosa cells.

Human reproduction (Oxford, England)·2020
Same author

Response to Wang et al. Re: How to choose and compare between radiofrequency ablation and transarterial chemoembolization for recurrent hepatocellular carcinoma?

HPB : the official journal of the International Hepato Pancreato Biliary Association·2017
Same author

The 20 faces of the fourth component of complement.

Immunology today·2014
Same author

Natural killer T cell defects in multiple myeloma and the impact of lenalidomide therapy.

Clinical and experimental immunology·2013
Same author

Chylous leakage post mastectomy and axillary clearance: clinical aspect, causes and review of literature.

The Medical journal of Malaysia·2013
Same author

Ex-vivo analysis of human natural killer T cells demonstrates heterogeneity between tissues and within established CD4(+) and CD4(-) subsets.

Clinical and experimental immunology·2013
Same journal

Microbial-derived polyphenol metabolites and the gut microbiota: A scoping review of clinical studies.

The Journal of nutrition·2026
Same journal

Hesperidin as an Emerging Nutraceutical in Modern Health and Preventive Medicine: A Narrative Review.

The Journal of nutrition·2026
Same journal

Short-Chain Fatty Acids in Livestock and Aquatic Animals: Metabolic Divergence, Physiological Functions, and Product Development.

The Journal of nutrition·2026
Same journal

Immunomodulatory properties of choline and its dietary forms throughout the lifespan.

The Journal of nutrition·2026
Same journal

Oat-rich low-gluten diet modulates plasma short-chain fatty acids without significant changes in fecal microbiome or inflammatory markers - a randomized clinical trial in people with cardiometabolic risk.

The Journal of nutrition·2026
Same journal

Diet and Cognitive Function in Aging: An Individual Participant Data Meta-Analysis from Eight Cohorts in Europe and the United States.

The Journal of nutrition·2026
See all related articles

Vitamin E may protect against heart disease by preventing LDL oxidation and inflammation. This review integrates current knowledge on atherosclerosis and vitamin E

Area of Science:

  • Cardiovascular Science
  • Nutritional Science
  • Biochemistry

Background:

  • Atherosclerosis is a chronic inflammatory disease driven by endothelial injury and LDL oxidation.
  • Oxidized LDL triggers inflammatory responses, leading to plaque formation and lumen narrowing.
  • Vitamin E's role in preventing heart disease has been debated but is gaining support.

Purpose of the Study:

  • To review the biological functions of vitamin E in the context of atherogenesis.
  • To integrate current knowledge on atherosclerosis with vitamin E's protective mechanisms.
  • To provide evidence supporting vitamin E's efficacy in preventing heart disease.

Main Methods:

  • Review of existing epidemiologic studies and clinical trials.
  • Integration of current knowledge on atherogenesis and vitamin E's biological functions.

Related Experiment Videos

  • Analysis of vitamin E's effects on LDL oxidation, inflammation, and vascular cell functions.

    • Main Results:

    • Vitamin E retards LDL oxidation and inhibits smooth muscle cell proliferation.
    • It inhibits platelet aggregation and the expression of adhesion molecules.
    • Vitamin E potentiates prostacyclin release and attenuates leukotriene synthesis.

    Conclusions:

    • Vitamin E demonstrates protective effects against atherosclerosis development.
    • Its biological functions align with mechanisms that prevent cardiovascular disease.
    • Evidence supports vitamin E as a potential therapeutic agent for heart disease.