Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biotin deficiency in chicks fed a wheat-based diet

M Frigg, G Brubacher

    International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. Journal International De Vitaminologie Et De Nutrition
    |January 1, 1976
    PubMed
    Summary

    Wheat-based diets cause severe biotin deficiency in chicks. Supplementation with 50 mug/kg partially reduced symptoms, while 300 mug/kg fully restored growth and biotin levels.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    About the metabolism of tubercle bacilli; systematic studies on the effect of primary aromatic amines on the growth of tubercle bacilli.

    Helvetica chimica acta·2010
    Same author

    An immunohistochemical study of the distribution of biotin in tissues of pigs and chickens.

    Research in veterinary science·1998
    Same author

    Tissue content of alpha-tocopherol and oxidative stability of broilers receiving dietary alpha-tocopheryl acetate supplement for various periods pre-slaughter.

    British poultry science·1997
    Same author

    Meta-analyses/meta-projects: a small but relevant contribution by Sight and Life to the prevention of vitamin A deficiency.

    European journal of clinical nutrition·1996
    Same author

    Effects of vitamin E on mammary and blood leukocyte function, with emphasis on chemotaxis, in periparturient dairy cows.

    American journal of veterinary research·1996
    Same author

    Color coordinates for assessment of dietary vitamin E effects on beef color stability.

    Journal of animal science·1996

    Area of Science:

    • Avian nutrition
    • Nutritional biochemistry
    • Animal science

    Background:

    • Biotin (vitamin B7) is essential for chick growth and development.
    • Wheat-based diets can potentially lead to biotin deficiency in poultry.
    • Understanding optimal biotin levels is crucial for preventing deficiency symptoms.

    Purpose of the Study:

    • To investigate the effects of a wheat-based diet on biotin levels in chicks.
    • To evaluate the efficacy of different biotin supplementation levels in preventing deficiency.
    • To establish reliable diagnostic parameters for subclinical biotin deficiency.

    Main Methods:

    • Chicks were fed a wheat-based diet and divided into three groups: no supplementation (group 1), 50 mug/kg biotin (group 2), and 300 mug/kg biotin (group 3).
    • Biotin deficiency symptoms, growth, plasma biotin levels, and liver biotin concentrations were monitored.
    • Data were analyzed to compare the effects of different dietary biotin levels.

    Main Results:

    • Group 1 chicks exhibited severe biotin deficiency symptoms by 3-4 weeks.
    • Group 2 showed partial symptom reduction, while Group 3 exhibited near-complete recovery and normal growth.
    • Plasma and liver biotin levels were significantly lower in deficient groups (1 and 2) compared to the supplemented group (3).

    Conclusions:

    • Wheat-based diets can induce significant biotin deficiency in chicks.
    • Biotin supplementation is effective in mitigating deficiency symptoms and restoring normal levels.
    • Plasma and liver biotin concentrations serve as reliable indicators for diagnosing subclinical biotin deficiency in chicks.

    Related Experiment Videos