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Cyclosporiasis in a traveler returning from South America
D Drenaggi1, O Cirioni, A Giacometti
1Institute of Infectious Diseases and Public Health, University of Ancona, Italy.
Abstract:
Cyclospora is a coccidian, previously referred to as a cyanobacterium-like body, with an epidemiology similar to that of Cryptosporidium parvum. In recent years, several studies have shown that Cyclospora is not a rare opportunistic pathogen but rather is the cause of common, worldwide intestinal infections in healthy adults and children. Previous reports of diarrhea resulting from Cyclospora sp. have been linked to travelers and immunocompromised patients. The species has a worldwide distribution. Although Cyclospora infection has been reported from Southeast Asia, Papua New Guinea, Indonesia, India, Pakistan, Nepal, the Middle East, North Africa, the United Kingdom, the Caribbean, the United States, Central America, and South America, the true prevalence of this parasite in any population is unknown. The parasite is associated with prolonged self-limiting and relapsing watery diarrhea, anorexia, fatigue, and sometimes myalgia. Fever is infrequent.
Insights
Cyclospora, a coccidian parasite, causes common worldwide intestinal infections in healthy individuals, not just rare opportunistic cases. This pathogen leads to prolonged diarrhea, fatigue, and anorexia, with a global distribution and unknown prevalence.
Area of Science:
- Medical Parasitology
- Infectious Diseases
- Public Health
Background:
- Cyclospora, a coccidian parasite, was previously misidentified as a cyanobacterium-like body.
- Its epidemiology shares similarities with Cryptosporidium parvum, another significant intestinal pathogen.
Observation:
- Recent studies indicate Cyclospora is a common cause of intestinal infections globally.
- These infections affect both healthy adults and children, challenging previous notions of it being a rare opportunistic pathogen.
- Reported cases were previously linked primarily to travelers and immunocompromised individuals.
Findings:
- Cyclospora species are distributed worldwide, with documented occurrences across Asia, Oceania, the Middle East, Africa, Europe, and the Americas.
- The true prevalence of Cyclospora infection in any given population remains undetermined.
- Infection symptoms include prolonged, relapsing watery diarrhea, anorexia, fatigue, and myalgia; fever is uncommon.
Implications:
- Increased recognition of Cyclospora as a common enteric pathogen is crucial for accurate diagnosis and public health surveillance.
- Understanding its global distribution and prevalence is essential for developing effective prevention and control strategies.
- Further research is needed to elucidate transmission routes and risk factors in diverse populations.
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