Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thyroid carcinoma

K Seta, S Takahashi

    International Surgery
    |October 1, 1976
    PubMed
    Summary

    Latent thyroid carcinoma is common, found in 15.7% of autopsies, with most tumors being small papillary adenocarcinomas. These small thyroid cancers may have inhibited growth, especially in hyperthyroid patients.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Quasimonochromatic white light fringe interferometer.

    Applied optics·2010
    Same author

    Distance meter utilizing the intermode beat of a He-Ne laser.

    Applied optics·2010
    Same author

    Stabilization of multiwavelength infrared lasers.

    Applied optics·2010
    Same author

    WWOX, the tumour suppressor gene affected in multiple cancers.

    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society·2009
    Same author

    Generation of self-pumped phase conjugation from the -c face of BaTiO3 with femtosecond pulses.

    Applied optics·2008
    Same author

    Spatial-Frequency Response of Photorefractive Phase Conjugators with Ce:BaTiO(3).

    Applied optics·2008

    Area of Science:

    • Endocrinology
    • Oncology
    • Pathology

    Background:

    • Thyroid carcinoma is a significant health concern.
    • Understanding the prevalence and characteristics of latent thyroid carcinoma is crucial for diagnosis and treatment.
    • Previous studies have not fully elucidated the clinical significance of small, incidentally discovered thyroid tumors.

    Purpose of the Study:

    • To determine the prevalence of latent thyroid carcinoma in routine autopsies.
    • To characterize the pathological subtypes and size distribution of these latent tumors.
    • To investigate the clinical significance and growth patterns of small thyroid carcinomas, particularly in the context of hyperthyroidism.

    Main Methods:

    • Histological examination of serial sections of thyroid glands from 379 consecutive autopsies.
    • Classification of detected thyroid carcinomas by subtype (papillary, follicular, trabecular, sclerosing).
    • Measurement of tumor size and correlation with clinical conditions like hyperthyroidism.

    Main Results:

    • Latent thyroid carcinoma was detected in 15.7% of examined thyroid glands.
    • Papillary adenocarcinoma was the most common subtype (76.3%), followed by follicular adenocarcinoma (22.0%).
    • Sclerosing carcinomas were often small, with 90% measuring less than 5 mm; similarly, carcinomas associated with hyperthyroidism were typically under 1 cm, with 70% under 5 mm.

    Conclusions:

    • Latent thyroid carcinoma is frequently found incidentally during autopsies.
    • The majority of these incidentally detected thyroid cancers are small, suggesting a potentially indolent or inhibited growth pattern.
    • The findings suggest that excessive thyroid hormone levels, as seen in hyperthyroidism, may inhibit the growth and proliferation of certain thyroid carcinomas.

    Related Experiment Videos