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[Studies on a new type of all-solid-state atropine ion-selective electrode]
Yao Xue Xue Bao = Acta Pharmaceutica Sinica
|January 1, 1996
Summary
A novel all-solid-state atropine ion-selective electrode was developed using urea-formaldehyde resin and an atropine ion-pair complex. This stable electrode offers reliable potentiometric determination of atropine in pharmaceutical samples.
Area of Science:
- Electrochemistry
- Analytical Chemistry
- Materials Science
Context:
- Development of ion-selective electrodes (ISEs) is crucial for accurate chemical analysis.
- Existing atropine detection methods may have limitations in stability or application.
- Solid-state electrodes offer advantages in handling and longevity.
Purpose:
- To construct a new all-solid-state atropine ion-selective electrode.
- To investigate the electrochemical properties and performance of the developed electrode.
- To evaluate its suitability for determining atropine in pharmaceutical preparations.
Summary:
- A silver/silver chloride (Ag/AgCl) solid-state electrode was fabricated using urea-formaldehyde resin and potassium chloride (KCl).
- This Ag/AgCl electrode served as a substrate for an all-solid-state atropine ion-selective electrode incorporating atropine tetraphenylborate ion-pair complex.
- The electrode demonstrated good stability and efficacy for the potentiometric determination of atropine.
Impact:
- Provides a stable and reliable method for atropine quantification in pharmaceutical formulations.
- Contributes to advancements in ion-selective electrode technology for drug analysis.
- Facilitates improved quality control and research in pharmaceutical chemistry.