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Updated: Aug 8, 2026

Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
Published on: February 12, 2015
Targeting early antecedents to prevent tobacco smoking: findings from an epidemiologically based randomized field
1Department of Mental Hygiene, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Md. 21224, USA.
Objectives:
This study examined whether interventions aimed at aggressive/disruptive classroom behavior and poor academic achievement would reduce the incidence of initiation of smoking.
Methods:
An epidemiologically based, universal randomized preventive trial involved 2311 children in 2 classroom-based preventive interventions or controls. Each intervention was directed at 1 of the aforementioned 2 antecedents over first and second grades in 19 urban schools.
Results:
Smoking initiation was reduced in both cohorts for boys assigned to the behavioral intervention.
Conclusions:
Targeting early risk antecedents such as aggressive behavior appears to be an important smoking prevention strategy.
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