Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Germinal tumor metastases. Case report]

C Lebrun1, P Girard, P Paquis

  • 1Service de Neurologie, Hôpital Pasteur, Nice.

Revue Neurologique
|October 17, 1998
PubMed
Summary

Intracranial germinoma, a common brain tumor, often presents with sudden high pressure inside the skull. Radiation therapy is standard, but chemotherapy offers a promising alternative for treating this radiosensitive tumor.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cost-utility of oral methylprednisolone in the treatment of multiple sclerosis relapses: Results from the COPOUSEP trial.

Revue neurologique·2021
Same author

Atypical myelitis in patients with multiple sclerosis: Characterization and comparison with typical multiple sclerosis and neuromyelitis optica spectrum disorders.

Multiple sclerosis (Houndmills, Basingstoke, England)·2020
Same author

Immunization and multiple sclerosis: Recommendations from the French Multiple Sclerosis Society.

Revue neurologique·2019
Same author

Digestive side-effects with teriflunomide: Thoughts on lactose.

Revue neurologique·2018
Same author

Inaugural tumor-like multiple sclerosis: clinical presentation and medium-term outcome in 87 patients.

Journal of neurology·2018
Same author

Demyelinating diseases.

Revue neurologique·2018

Area of Science:

  • Neuro-oncology
  • Pediatric oncology

Background:

  • Germinoma represents the most common intracranial germ-cell tumor.
  • Initial symptoms frequently involve acute intracranial hypertension.

Observation:

  • Magnetic resonance imaging (MRI) findings for germinoma are often non-specific.
  • Stereotactic surgery is typically the initial intervention before definitive treatment.
  • Metastasis, though rare, can occur via infiltration or cerebrospinal fluid pathways.

Findings:

  • Abdominal and pelvic metastases are observed in approximately 10% of patients with ventriculosomatic shunts.
  • Germinoma exhibits significant radiosensitivity, making radiation therapy a primary treatment modality.
  • Chemotherapy presents a viable alternative treatment option.

Related Experiment Videos

Implications:

  • Understanding germinoma's metastatic potential is crucial, especially in patients with shunts.
  • The radiosensitivity of germinoma supports radiation therapy as a standard treatment.
  • Chemotherapy offers a potentially less invasive or alternative therapeutic strategy for intracranial germinoma.