Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypertensive pancreatic sphincter

G A Lehman1, S Sherman

  • 1Department of Medicine, Indiana University Medical Center, Indianapolis, USA.

Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie
|October 17, 1998
PubMed
Summary

Major papilla pancreatic sphincter dysfunction causes pain and pancreatitis. Endoscopic manometry is key for diagnosis, though noninvasive tests are less reliable. Treatment strategies vary, with pancreatic sphincterotomy carrying higher pancreatitis risks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Profile of and risk factors for early unplanned readmissions in patients with acute necrotizing pancreatitis.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]·2023
Same author

Complexation reduces nickel toxicity to purple sea urchin embryos (Strongylocentrotus purpuratus), a test of biotic ligand principles in seawater.

Ecotoxicology and environmental safety·2021
Same author

Should we be imaging lymph nodes at initial diagnosis of early-stage mycosis fungoides? Results from the PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) international study.

The British journal of dermatology·2020
Same author

Unilesional mycosis fungoides is associated with increased expression of microRNA-17~92 and T helper 1 skewing.

The British journal of dermatology·2018
Same author

Grover disease and bullous pemphigoid: a clinicopathological study of six cases.

Clinical and experimental dermatology·2018
Same author

Relating the Electrical Resistance of Fresh Concrete to Mixture Proportions.

Advances in civil engineering materials·2018

Area of Science:

  • Gastroenterology
  • Surgical Endoscopy

Background:

  • Major papilla pancreatic sphincter dysfunction is a subtype of sphincter of Oddi dysfunction.
  • It frequently causes pancreatitis or pancreatic-type pain.

Purpose of the Study:

  • To review the diagnosis and management of major papilla pancreatic sphincter dysfunction.
  • To discuss the controversies and risks associated with therapeutic interventions.

Main Methods:

  • Endoscopic manometry during endoscopic retrograde cholangiography (ERC) is the gold standard for diagnosis.
  • Secretin-stimulated ultrasound is a less sensitive noninvasive alternative.

Main Results:

  • Elevated pancreatic basal sphincter pressure is found in two-thirds of patients.
  • Biliary sphincterotomy may suffice, but pancreatic sphincter evaluation is needed for persistent symptoms.
  • Pancreatic sphincterotomy has similar complication rates to biliary sphincterotomy, but a 2-4x higher pancreatitis risk.

Conclusions:

  • Treatment decisions for pancreatic and biliary sphincters require careful consideration.
  • Prophylactic pancreatic stenting can reduce post-sphincterotomy pancreatitis by approximately 50%.

Related Experiment Videos