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Laryngeal paralysis-polyneuropathy complex in young Rottweilers

O M Mahony1, K E Knowles, K G Braund

  • 1Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA. omahony@infonet.tufts.edu

Journal of Veterinary Internal Medicine
|October 17, 1998
PubMed
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Five Rottweiler puppies experienced breathing difficulties and limb weakness due to a hereditary polyneuropathy. This neurological condition affecting nerves and muscles led to laryngeal paralysis and a poor prognosis.

Area of Science:

  • Veterinary Neurology
  • Canine Genetics

Background:

  • Laryngeal paralysis in young dogs can indicate underlying neurological disorders.
  • Early identification is crucial for appropriate management and prognosis.

Observation:

  • Five Rottweiler puppies from unrelated litters presented with inspiratory stridor at 11-13 weeks of age.
  • Clinical signs included tetraparesis and, in some, bilateral lenticular cataracts.
  • Laryngeal examination revealed paralysis in all affected puppies.

Findings:

  • Electrodiagnostic testing showed denervation potentials in appendicular and laryngeal muscles.
  • Histopathology confirmed neurogenic muscular atrophy and peripheral nerve degeneration.
  • Autopsies ruled out spinal cord or nerve root abnormalities, supporting a diagnosis of polyneuropathy.

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Implications:

  • Findings suggest a hereditary polyneuropathy similar to that seen in Dalmatians.
  • Neurological evaluation is recommended for young dogs with laryngeal paralysis.
  • The condition has a poor prognosis, highlighting the need for further research into genetic factors.