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Laryngeal paralysis-polyneuropathy complex in young Rottweilers
O M Mahony1, K E Knowles, K G Braund
1Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA. omahony@infonet.tufts.edu
Journal of Veterinary Internal Medicine
|October 17, 1998
Summary
Five Rottweiler puppies experienced breathing difficulties and limb weakness due to a hereditary polyneuropathy. This neurological condition affecting nerves and muscles led to laryngeal paralysis and a poor prognosis.
Area of Science:
- Veterinary Neurology
- Canine Genetics
Background:
- Laryngeal paralysis in young dogs can indicate underlying neurological disorders.
- Early identification is crucial for appropriate management and prognosis.
Observation:
- Five Rottweiler puppies from unrelated litters presented with inspiratory stridor at 11-13 weeks of age.
- Clinical signs included tetraparesis and, in some, bilateral lenticular cataracts.
- Laryngeal examination revealed paralysis in all affected puppies.
Findings:
- Electrodiagnostic testing showed denervation potentials in appendicular and laryngeal muscles.
- Histopathology confirmed neurogenic muscular atrophy and peripheral nerve degeneration.
- Autopsies ruled out spinal cord or nerve root abnormalities, supporting a diagnosis of polyneuropathy.
Implications:
- Findings suggest a hereditary polyneuropathy similar to that seen in Dalmatians.
- Neurological evaluation is recommended for young dogs with laryngeal paralysis.
- The condition has a poor prognosis, highlighting the need for further research into genetic factors.