Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Early cardiac changes after menopause

G Schillaci1, P Verdecchia, C Borgioni

  • 1Ospedale "Beato G. Villa," Divisione di Medicina, Città della Pieve, and Ospedale "R. Silvestrini," Dipartimento di Cardiologia, Perugia, Italy.

Hypertension (Dallas, Tex. : 1979)
|October 17, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Epidemiology of emergency calls for time-dependent acute illnesses during COVID-19 outbreak in Umbria region (Italy).

Annali di igiene : medicina preventiva e di comunita·2020
Same author

Reply.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2020
Same author

Celocentesis for early prenatal diagnosis of hemoglobinopathy.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2020
Same author

Hyperuricemia and Risk of Cardiovascular Outcomes: The Experience of the URRAH (Uric Acid Right for Heart Health) Project.

High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension·2020
Same author

Increased Bone Resorption: A Possible Pathophysiological Link Between Hypovitaminosis D and Peripheral Arterial Disease.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2016
Same author

Brain natriuretic peptide as a cardiac marker of transient radiotherapy-related damage in left-sided breast cancer patients: A prospective study.

Breast (Edinburgh, Scotland)·2015
Same journal

Brain Iron in Nucleus Accumbens and Cognitive Function in Preeclampsia.

Hypertension (Dallas, Tex. : 1979)·2026
Same journal

Hypertension Treatment Intentions: A Health Belief Model Analysis.

Hypertension (Dallas, Tex. : 1979)·2026
Same journal

Changes in Retinal Microvasculature During Healthy Pregnancy Measured by AO.

Hypertension (Dallas, Tex. : 1979)·2026
Same journal

Longitudinal Maternal IgG and IgA Glycosylation Profiles in Pregnancy Reveal Early Immune Alterations in Placenta-Related Complications: The Rotterdam Periconception Cohort.

Hypertension (Dallas, Tex. : 1979)·2026
Same journal

Blood Pressure Variability and Outcomes Across Antihypertensive Regimens.

Hypertension (Dallas, Tex. : 1979)·2026
Same journal

Rural Health and Health Disparities in Hypertension Management: A Scientific Statement From the American Heart Association.

Hypertension (Dallas, Tex. : 1979)·2026
See all related articles

Menopause is linked to reduced blood pressure regulation and impaired heart function, increasing cardiovascular risk. These changes occur regardless of hypertension status.

Area of Science:

  • Cardiology
  • Reproductive Endocrinology

Background:

  • Increased cardiovascular risk is observed post-menopause, but underlying mechanisms remain unclear.
  • Menopause may influence cardiac structure and function, independent of blood pressure levels.

Purpose of the Study:

  • To investigate left ventricular (LV) structural and functional adaptations in women after menopause.
  • To compare these adaptations in both normotensive and hypertensive women.

Main Methods:

  • Case-control study matching premenopausal and postmenopausal women by age, BMI, and blood pressure.
  • Utilized 24-hour ambulatory blood pressure monitoring and M-mode echocardiography.

Main Results:

  • Postmenopausal women exhibited blunted nocturnal blood pressure dipping in both normotensive and hypertensive groups.

Related Experiment Videos

  • Menopause was associated with increased LV relative wall thickness and reduced midwall fractional shortening.
  • These cardiac changes were observed independently of hypertension.

    • Conclusions:

    • Menopause is associated with impaired cardiovascular regulation, including reduced nocturnal blood pressure fall.
    • Menopause induces adverse left ventricular remodeling and systolic dysfunction.
    • Findings highlight menopause as a critical period for cardiovascular adaptation and risk assessment.