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Prognostic factors in gastric cancer evaluated by using Cox regression model
G Ghiandoni1, M B Rocchi, P Signoretti
1Istituto di Biomatematica, Università degli Studi, Urbino.
Objective:
To identify the most relevant short-term predictor variables in gastric cancer removal.
Experimental Design:
A retrospective survival analysis executed by using the Cox regression model; the follow-up period is included between 18 and 90 months.
Setting:
A district general hospital surgery unit: "Divisione di Chirurgia Generale, Ospedale Civile di Urbino" (Marche, Italy).
Subjects:
One hundred and twenty nine consecutive patients operated for gastric cancer.
Interventions:
Surgery (total or subtotal gastrectomy).
Main Outcome Measure:
Survival times.
Results:
Lymph node involvement (N) (p < 0.0001), cancer intraparietal extension (T) (p < 0.001) and the age of the patients (p < 0.05) have been recognized as significant prognostic factors.
Conclusions:
Results show that the short-term prognosis largely depends on both the earliness of the diagnosis and the age of the patients.