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[Association of Biermer's anemia and gastric carcinoid tumors]
C Boudray1, C Grange, I Durieu
1Service de médecine interne, centre hospitalier Lyon-Sud, Pierre-Bénite, France.
Background:
The occurrence of gastric carcinoid tumors during the cure of pernicious anemia has been reported in the literature. Concerning a new case, we review physiopathological data of this infrequent association.
Case Report:
We report the case of a 47-year-old women with pernicious anemia in which gastroscopy found two small tumors developed from enterochromaffin-like cells.
Conclusion:
These tumors are usually latent and developed from enterochromaffin-like cells. The pathologic and histologic diagnosis is based on positive chromogranin A immunomarking. The physiopathological mechanism studies are in favour of the predominant part of hypergastrinemia following achlorhydria. Usually, evolution is benign and surgical or endoscopic resection recommended.