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[Acute disseminated encephalomyelitis preceding cutaneous lupus]
F Dubreuil1, P Cabre, D Smadja
1Service de neurologie, CHU de Fort-de-France, Martinique.
Study Design:
A case of acute disseminated encephalomyelitis (ADEM) preceding the features of cutaneous lupus is reported.
Objectives:
To suggest that ADEM and cutaneous lupus are pathophysiologically related.
Summary Of The Background Data:
Neurological complications of systemic lupus erythematosus are common. However, demyelinative central nervous system manifestations are rare, and restricted to neuromyelitis optica (NMO). NMO is thought to be a partial form of ADEM.
Methods:
A clinical, neuroradiological and immunological study was performed in this case.
Results:
ADEM was diagnosed in a young black female. Three years later, she developed a cutaneous lupus without hypocomplementemia.
Conclusion:
A relationship between ADEM and cutaneous lupus is suggested. The normal serum complement level in our patient might be a predisposing factor for the development of ADEM.