Examination of poliovaccines for the presence of SV40 sequences
Related Experiment Video
Updated: Oct 28, 2026
Particle Agglutination Method for Poliovirus Identification
Published on: April 20, 2011
D V Sangar1, D J Wood, P D Minor
1National Institute for Biological Standards and Control, Potters Bar, Herts, UK.
Abstract:
Batches of monovalent oral poliovirus vaccine bulks previously screened for infectious SV40 by cell culture methods and used in the United Kingdom from 1971-96 in trivalent oral poliovirus vaccine have now been examined by a newly developed PCR for the presence of SV40 sequences. Up to April 1997, over 190 batches have been examined. SV40 sequences were not detected in any of the vaccines. This provides additional assurance that oral poliovirus vaccines used in the U.K. from 1971 are free of SV40 contamination.
More Related Videos
05:22Electrophoretic Analysis of Replication Through Structure-Prone DNA Repeats Within the SV40-Based Human Episome
Published on: September 13, 2024
11:09EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay
Published on: September 11, 2016
