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Pregnancies complicated by diabetic proliferative retinopathy
F F Lauszus1, P L Grøn, J G Klebe
1Gynecological and Obstetrical Unit, Dept. Y, Skejby Hospital, Aarhus, Denmark.
Acta Obstetricia Et Gynecologica Scandinavica
|October 17, 1998
Summary
Diabetic women with proliferative retinopathy and albuminuria face higher risks of preterm birth and low birthweight. Nephropathy, not retinopathy, significantly impacts perinatal morbidity in these pregnancies.
Area of Science:
- Reproductive Medicine
- Ophthalmology
- Endocrinology
Background:
- Focuses on insulin-dependent diabetic women with proliferative retinopathy.
- Examines retinal and pregnancy outcomes.
- Assesses the impact of albuminuria on maternal and perinatal morbidity.
Purpose of the Study:
- To investigate retinal and pregnancy outcomes in insulin-dependent diabetic women with proliferative retinopathy.
- To evaluate the effect of albuminuria on morbidity in these pregnancies.
Main Methods:
- Retrospective study of 26 women with known proliferative retinopathy before pregnancy.
- Analysis of ophthalmic, obstetric, and pediatric records from pre-pregnancy through postpartum.
- Assessment of perinatal and maternal morbidity.
Main Results:
- 27% of pregnancies were preterm; 19% had serious neonatal morbidity; 88% perinatal survival.
- Low birthweight was linked to nephropathy and retinopathy.
- Hemorrhage, maculopathy, or glaucoma occurred in 54% of women; two developed unilateral blindness.
Conclusions:
- Perinatal morbidity is associated with nephropathy, not solely retinopathy.
- Albuminuria's role in morbidity requires further investigation.
- Hemorrhage, maculopathy, and glaucoma incidence were similar across specific retinopathy classifications.