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Complete cDNA sequence of the HLA-DRB1*09012 allele
N Martínez-Quiles1, J M Martín-Villa, S Ferre-López
1Department of Immunology, Hospital 12 de Octubre, Universidad Complutense, Madrid, Spain.
Abstract:
Sequencing studies of HLA class II molecules have focused almost exclusively on exon 2. In this study the complete cDNA sequence of the DRB1*09012 allele is reported for the first time. This sequence was previously only partially published. In the DR9 antigen, two synonymous allelic variants (DRB1*09011 and 09012) were officially recognized, though it was later found that the first one contained an error and both sequences were, thus, identical.