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Subclinical thyroid disease in the elderly

M H Samuels1

  • 1Division of Endocrinology, Diabetes, and Clinical Nutrition, Oregon Health Sciences University, Portland 97201, USA.

Thyroid : Official Journal of the American Thyroid Association
|October 20, 1998
PubMed
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Subclinical thyroid disease, including hypothyroidism and hyperthyroidism, is common in older adults. Careful risk assessment is crucial before treating these TSH level abnormalities.

Area of Science:

  • Endocrinology
  • Geriatric Medicine
  • Thyroidology

Background:

  • Sensitive thyrotropin (TSH) assays reveal subclinical thyroid dysfunction in the elderly.
  • Subclinical hypothyroidism affects 5-10% of older adults, more women; subclinical hyperthyroidism affects <2%.

Purpose of the Study:

  • To summarize the prevalence, causes, and risks of subclinical thyroid disease in the elderly.
  • To inform treatment decisions for subclinical thyroid dysfunction in older patients.

Main Methods:

  • Review of literature on subclinical thyroid disease in the elderly.
  • Analysis of prevalence, risk factors, and potential complications.

Main Results:

  • Subclinical hypothyroidism and hyperthyroidism are characterized by isolated TSH abnormalities.

Related Experiment Videos

  • Medications and iodine compounds may contribute to subclinical thyroid disease in the elderly.
  • Risks include progression to overt disease, cardiovascular issues, and osteoporosis.
  • Conclusions:

    • Treatment decisions for elderly patients with subclinical thyroid disease require individualized risk-benefit assessment.
    • Potential risks associated with subclinical hypothyroidism and hyperthyroidism necessitate careful monitoring and management.