Related Experiment Videos
[Inflammatory bowel disease--Crohn's disease]
Insights
Acute massive hemorrhage from Crohn's disease (CD) occurs in 3.0% of cases, often critically impacting the small intestine. Careful treatment is advised due to the potential for severe gastrointestinal bleeding in CD patients.
Area of Science:
- Gastroenterology
- Internal Medicine
- Clinical Research
Context:
- Crohn's disease (CD) is a chronic inflammatory condition.
- Massive gastrointestinal hemorrhage is a rare but serious complication of CD.
- Understanding bleeding patterns in CD is crucial for patient management.
Purpose:
- To analyze the incidence and characteristics of acute massive hemorrhage in Crohn's disease.
- To identify common sites and patient demographics associated with severe bleeding in CD.
- To highlight the critical nature of massive bleeding in CD.
Summary:
- Acute massive hemorrhage occurred in 3.0% of Crohn's disease patients at our institution.
- A review of Japanese literature identified 40 CD patients with massive hemorrhage over 20 years, predominantly male (7:1 ratio).
- Small intestinal CD (90%) was most common, with bleeding primarily in the ileum (82.5%) and colon (12.5%).
Impact:
- This study underscores the occasional critical nature of acute massive hemorrhage in Crohn's disease.
- Findings emphasize the need for careful management and monitoring of CD patients at risk for severe gastrointestinal bleeding.
- Highlights the importance of considering the small intestine, particularly the ileum, as a common source of massive bleeding in CD.
Abstract:
Acute massive hemorrhage from CD occurred in 3.0% in our institution. Forty CD patients with massive hemorrhage were reported in last 20 years in Japan. The ratio of male to female was 7.0. Ninety percent of them complicated the small intestinal CD. Massive bleeding was seen mostly in the ileum (82.5%) and next was in the colon (12.5%). However massive gastrointestinal hemorrhage is not often complicated in Crohn's disease, acute massive hemorrhage is occasionally critical. Therefore it is considered that CD should be treated carefully.