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[Inflammatory bowel disease--Crohn's disease]

H Matake1, T Matsui, T Yao

  • 1Department of Gastroenterology, Fukuoka University Chikushi Hospital.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|October 22, 1998
PubMed
Summary

Acute massive hemorrhage from Crohn's disease (CD) occurs in 3.0% of cases, often critically impacting the small intestine. Careful treatment is advised due to the potential for severe gastrointestinal bleeding in CD patients.

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Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Clinical Research

Context:

  • Crohn's disease (CD) is a chronic inflammatory condition.
  • Massive gastrointestinal hemorrhage is a rare but serious complication of CD.
  • Understanding bleeding patterns in CD is crucial for patient management.

Purpose:

  • To analyze the incidence and characteristics of acute massive hemorrhage in Crohn's disease.
  • To identify common sites and patient demographics associated with severe bleeding in CD.
  • To highlight the critical nature of massive bleeding in CD.

Summary:

  • Acute massive hemorrhage occurred in 3.0% of Crohn's disease patients at our institution.
  • A review of Japanese literature identified 40 CD patients with massive hemorrhage over 20 years, predominantly male (7:1 ratio).
  • Small intestinal CD (90%) was most common, with bleeding primarily in the ileum (82.5%) and colon (12.5%).

Impact:

  • This study underscores the occasional critical nature of acute massive hemorrhage in Crohn's disease.
  • Findings emphasize the need for careful management and monitoring of CD patients at risk for severe gastrointestinal bleeding.
  • Highlights the importance of considering the small intestine, particularly the ileum, as a common source of massive bleeding in CD.

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