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Related Experiment Videos

Renal transplantation into augmented bladders

Y Yamazaki1, K Tanabe, T Ota

  • 1Department of Urology, Tokyo Women's Medical College, Japan.

International Journal of Urology : Official Journal of the Japanese Urological Association
|October 22, 1998
PubMed
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Renal transplantation into augmented bladders is feasible and successful, though urinary tract infections are a concern. Pretransplant bladder reconstruction is recommended for optimal graft function and continence.

Area of Science:

  • Urology
  • Transplantation Surgery
  • Nephrology

Background:

  • Urinary bladder augmentation is increasingly used for dysfunctional bladders in renal transplant recipients.
  • The safety and efficacy of renal transplantation into augmented bladders remain under investigation, particularly regarding infection and graft survival.
  • This study reports on four cases of renal transplantation into augmented bladders.

Purpose of the Study:

  • To evaluate the outcomes of renal transplantation in patients with augmented bladders.
  • To assess graft function, urinary continence, and complications in this patient population.

Main Methods:

  • Retrospective review of 1275 renal transplants, identifying 4 cases with prior or subsequent bladder augmentation.
  • Bladder augmentation utilized ileal segments or ureteral tissue.

Related Experiment Videos

  • Graft function monitored via serum creatinine; bladder capacity and function assessed with fluorocystometrograms.

    • Main Results:

    • Satisfactory posttransplant renal function was observed in all patients, with no proteinuria.
    • Three out of four patients achieved a large-capacity, low-pressure bladder and continence with clean intermittent catheterization.
    • Three patients experienced posttransplant pyelonephritis, but no other significant complications were noted.

    Conclusions:

    • Renal transplantation into augmented bladders can be performed safely with good outcomes.
    • Pretransplant bladder reconstruction is advised to preserve graft function and enhance urinary continence.
    • Urinary tract infection is a significant consideration requiring careful management.