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Bilateral temporal lobe necrosis after radiotherapy: confounding SPECT results
B de Vries1, M J Taphoorn, J W van Isselt
1Department of Neurology, University Hospital Utrecht, The Netherlands.
Neurology
|October 22, 1998
Abstract:
A patient with seizures and a contrast-enhancing temporal lesion after radiation therapy for a chondrosarcoma of the nasal septum is described. To differentiate between radiation necrosis and recurrent tumor, thallium-201 (201Tl) SPECT was used. 201Tl SPECT revealed high local accumulation suggesting tumor growth; however, pathologic examination demonstrated focal necrosis with reactive changes but without tumor. The 201Tl SPECT findings in this patient demonstrate a possible diagnostic pitfall in differentiating recurrent tumor from radiation necrosis.