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Devic's neuromyelitis optica: a prospective study of seven patients treated with prednisone and azathioprine
R N Mandler1, W Ahmed, J E Dencoff
1Department of Neurology, The University of New Mexico Health Sciences Center, Albuquerque 87131, USA.
Neurology
|October 22, 1998
Abstract:
Seven newly diagnosed patients with Devic's neuromyelitis optica were treated with long-term prednisone and azathioprine, and were followed every 2 months for at least 18 months. Their Expanded Disability Status Scale score improved significantly (mean at baseline, 9; mean at 18 months, 3; p < 0.005), and no relapses occurred for more than 18 months. Multicenter controlled studies are needed to prove the efficacy of this therapeutic regimen.