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Hypoechoic periportal cuffing in acute myeloid leukemia
1Department of Radiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Journal of Clinical Ultrasound : JCU
|October 23, 1998
Summary
Hypoechoic periportal cuffing, a rare ultrasound finding, was observed in a patient with acute myeloid leukemia. This finding resolved rapidly with chemotherapy, suggesting a link to the disease or its treatment.
Area of Science:
- Hepatology
- Oncology
- Radiology
Background:
- Acute myeloid leukemia (AML) can present with diverse clinical manifestations.
- Periportal cuffing is an ultrasound finding indicative of fluid accumulation or infiltration in the periportal space.
- The specific sonographic appearance of hypoechoic periportal cuffing in AML is not well-documented.
Observation:
- A case study involving a patient diagnosed with acute myeloid leukemia.
- The patient exhibited hypoechoic periportal cuffing on ultrasound, characterized by a hypoechoic area surrounding the portal vein and its branches.
- This sonographic abnormality was monitored during treatment.
Findings:
- The observed hypoechoic periportal cuffing was hypothesized to result from transient lymphedema due to lymphatic vessel obstruction or direct malignant cell infiltration.
- The sonographic abnormality demonstrated a complete resolution within two weeks of initiating chemotherapy.
- This suggests a reversible nature of the periportal changes in response to AML treatment.
Implications:
- This case highlights a potential, albeit uncommon, sonographic manifestation of acute myeloid leukemia.
- The rapid resolution of hypoechoic periportal cuffing with chemotherapy suggests its association with active disease or treatment-related effects.
- Further research may elucidate the precise mechanisms and diagnostic significance of this finding in AML patients.