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Related Experiment Video

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Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group

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Published on: August 16, 2017

Multiple sequence alignment in HTML: colored, possibly hyperlinked, compact representations

F Campagne¹, B Maigret

¹Laboratoire de Chimie théorique, Université Henri Poincaré Nancy I, UMR CNRS/UHP 7565, Vandoeuvre-les-Nancy, France. campagne@lctn.u-nancy.fr

Journal of Molecular Graphics & Modelling

|October 23, 1998

Summary

This study introduces two novel methods for representing protein sequence alignments as interactive HTML pages. These methods enhance accessibility for researchers, facilitating collaborative research and data visualization.

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An Integrated Approach for Microprotein Identification and Sequence Analysis

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

Area of Science:

Bioinformatics
Computational Biology
Structural Biology

Background:

Protein sequence alignments are crucial for various applications including structure prediction and protein engineering.
Current methods for accessing and visualizing these alignments online have limitations.
There is a need for accessible, network-based tools for biologists and chemists.

Purpose of the Study:

To develop novel methods for representing protein sequence alignments as colored, hyper-linked HTML pages.
To improve the accessibility and usability of protein alignment data for research and collaboration.
To create a WWW service for converting MSF alignment files to HTML.

Main Methods:

Developed two novel approaches for generating HTML representations of protein sequence alignments.
Method 1: Utilizes WWW browser image cache for efficient browsing of multiple alignments.
Method 2: Employs W3C-CSS1-style sheets for alignment rendering, requiring recent browsers.

Main Results:

Generated hyper-linked HTML pages for protein sequence alignments.
The first method allows efficient browsing by leveraging browser cache.
The second method offers a modern rendering approach using CSS.
Implemented these methods in the Viseur program, creating a WWW service for MSF to HTML conversion.

Conclusions:

The developed methods provide enhanced, web-based visualization of protein sequence alignments.
These tools facilitate easier access and collaborative research for biologists and chemists.
The Viseur WWW service simplifies the publication of alignment data online.