SLASH: a program for analysing the functional groups in molecules
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Updated: Oct 28, 2026

MALDI-ToF MS Method for the Characterization of Synthetic Polymers with Varying Dispersity and End Groups
Published on: October 3, 2025
1Zeneca Pharmaceuticals, Macclesfield, Cheshire, UK.
Abstract:
The program SLASH, which is designed to enable large numbers of compounds to be analysed in terms of the functional groups they contain, is described. The usefulness of the groups for analysing the activities of compounds tested in high-throughput biological screens is investigated. The functional group fragments are also studied as a means of determining similarity within groups of compounds.
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Mass Spectrometry: Aldehyde and Ketone Fragmentation
Introduction to Functional Groups
Functional groups are group of atoms with specific chemical properties that occur within organic molecules and sometimes denoted as “R”. Functional groups are found along the carbon backbone of macromolecules can form chains or rings of carbon atoms. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of common functional groups
The table below summarizes some of the major functional groups in organic chemistry. (The...
Overview of Advanced Functional Groups
Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.
Overview of Functional Groups
Functional Groups
Functional Groups
