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[Lactose in human nutrition]

M de Vrese¹, R Sieber, M Stransky

¹Institut für Physiologie und Biochemie der Ernährung, Bundesanstalt für Milchforschung, Kiel.

Schweizerische Medizinische Wochenschrift

|October 23, 1998

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Lactose intolerance occurs when lactase enzyme activity decreases, causing digestive issues. Many can still consume dairy in moderation, especially hard cheeses, which are vital calcium sources.

Area of Science:

Biochemistry
Gastroenterology
Human Physiology

Context:

Lactose, a milk disaccharide, is broken down by lactase (beta-galactosidase) into absorbable glucose and galactose.
Reduced lactase activity after infancy leads to lactose malabsorption and intolerance symptoms.
Lactose intolerance affects a significant portion of the adult population worldwide.

Purpose:

To explain the physiological basis of lactose intolerance.
To clarify the role of the lactase enzyme in lactose digestion.
To inform about dietary recommendations for individuals with lactose intolerance.

Summary:

Lactose intolerance is characterized by the inability to fully digest lactose due to diminished lactase enzyme activity.
Undigested lactose reaches the large intestine, causing symptoms like bloating, gas, and diarrhea.

Related Experiment Videos

While complete dairy avoidance is often advised, moderate consumption of milk and certain cheeses may be tolerated.

Impact:

Highlights the importance of dairy products as calcium sources for lactose-intolerant individuals.
Suggests that complete dairy exclusion may not be necessary for all lactose-intolerant people.
Emphasizes the need for personalized dietary management of lactose intolerance.