The frequency and functional impact of hypertension overlapping on hypertrophic cardiomyopathy: comparison between

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P P Dimitrow1, D Czarnecka, K Kawecka-Jaszcz

  • 12nd and 1st Department of Cardiology, Collegium Medicum Jagiellonian University, Kraków, Poland.

Journal of Human Hypertension
|October 23, 1998
PubMed

Insights

Hypertension is common in hypertrophic cardiomyopathy (HCM), especially in older adults. In younger patients with hypertrophic cardiomyopathy and hypertension (HTHCM), functional status is worse compared to those with HCM alone.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Clinical Research

Background:

  • Previous studies linked hypertension (HT) with decreased survival in elderly hypertrophic cardiomyopathy (HCM) patients.
  • The impact of co-occurring hypertension on functional status in younger HCM patients remained unclear.

Purpose of the Study:

  • To determine the frequency and age distribution of hypertension in a hypertrophic cardiomyopathy population.
  • To compare the New York Heart Association (NYHA) functional class in patients with hypertrophic cardiomyopathy and hypertension (HTHCM) versus those with HCM alone, across different age groups.

Main Methods:

  • Retrospective analysis of 123 hypertrophic cardiomyopathy patients.
  • Categorization into younger (<50 years) and older (>50 years) subgroups.
  • Comparison of NYHA functional classes between HTHCM and HCM patients within each subgroup.

Main Results:

  • Hypertension was present in 19.5% of HCM patients (24/123).
  • The prevalence of concomitant hypertension increased significantly with age, from 15.7% in younger patients to 38% in older patients.
  • Younger HTHCM patients exhibited significantly higher NYHA classes (2.19) compared to HCM patients (1.94) (P < 0.05).
  • In older patients, NYHA classes were comparable between HTHCM (2.13) and HCM (2.23) groups (P > 0.05).

Conclusions:

  • Hypertension is a frequent comorbidity in hypertrophic cardiomyopathy, particularly in older individuals.
  • The combination of hypertension and HCM significantly worsens functional capacity in younger patients.
  • In older patients, hypertension does not appear to further deteriorate functional status beyond that of HCM alone.
Abstract

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