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New diketopiperazines from the sponge Dysidea chlorea
X Fu1, M L Ferreira, F J Schmitz
1Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, Zealand, USA.
Journal of Natural Products
|October 24, 1998
Abstract:
Twelve new polychlorinated diketopiperazines (7-18), along with six known ones (1-6) and a known sterol (19), were isolated from the sponge Dysidea chlorea, collected from Yap, Federated States of Micronesia. The structures of dysamides I-T (7-18) were elucidated by spectroscopic methods, and one (8) was confirmed by chemical conversion. The stereochemistry of the dysamides is discussed.