Abietane diterpenoids from the cones of larix kaempferi
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Updated: Oct 28, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
1Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan.
Abstract:
Three new abietane-type diterpenes, 7alpha,15-dihydroxyabieta-8,11, 13-trien-18-al (1); 15,18-dihydroxyabieta-8,11,13-trien-7-one (2); and 18-nor-4,15-dihydroxyabieta-8,11,13-trien-7-one (3), were isolated from the cones of Larix kaempferi, together with three known diterpenes, abieta-8,11,13-trien-18-yl succinate, 16-nor-15-oxoabieta-8,11,13-trien-18-oic acid, and 7beta-hydroxyabieta-8,11,13-trien-18-oic acid. The structures of 1-3 were determined on the basis of chemical and spectral evidence.
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