Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Task-dependent deficits during object release in Parkinson's disease

A M Gordon1

  • 1Teachers College, Columbia University, 525 West 120th Street, New York, New York, 10027, USA.

Experimental Neurology
|October 24, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incidence of occult cleft palate on prenatal magnetic resonance images obtained for non-cleft indications.

International journal of oral and maxillofacial surgery·2022
Same author

Early weight gain in infants with Robin sequence after mandibular distraction.

International journal of oral and maxillofacial surgery·2022
Same author

<i>In situ</i> regeneration of <i>Pinus strobus</i> and <i>P. resinosa</i> in the Great Lakes forest communities of Canada.

Journal of vegetation science : official organ of the International Association for Vegetation Science·2020
Same author

Spatial and Temporal Variation in Soil Nitrous Oxide Emissions from a Rehabilitated and Undisturbed Riparian Forest.

Journal of environmental quality·2019
Same author

Erratum to: Riparian Land-Use and Rehabilitation: Impact on Organic Matter Input and Soil Respiration.

Environmental management·2015
Same author

Riparian land-use and rehabilitation: impact on organic matter input and soil respiration.

Environmental management·2014

Parkinson's disease (PD) patients show altered fingertip force control, especially during fast movements. Medication did not impact these force adjustments, highlighting task-specific impairments in PD.

Area of Science:

  • Neuroscience
  • Motor Control
  • Biomedical Engineering

Background:

  • Parkinson's disease (PD) is a neurodegenerative disorder affecting motor control.
  • Fingertip force regulation is crucial for object manipulation.
  • Understanding PD-related motor deficits requires examining specific task parameters.

Purpose of the Study:

  • To investigate fingertip force control during object replacement and release in individuals with Parkinson's disease.
  • To compare motor performance off and on medication.
  • To determine the influence of task speed on force regulation in PD.

Main Methods:

  • Eight subjects with Parkinson's disease (PD) and eight age-matched controls participated.
  • Participants performed object replacement and release tasks at preferred and maximal speeds.

Related Experiment Videos

  • Fingertip forces were measured using an instrumented object.

    • Main Results:

    • At preferred speeds, PD subjects showed similar force control to controls, unaffected by medication.
    • At maximal speeds, PD subjects exhibited significantly slower force decrease rates and longer durations.
    • Impaired force release was observed in PD subjects irrespective of medication status.

    Conclusions:

    • Motor impairments in Parkinson's disease are task-dependent, particularly evident during rapid movements.
    • Medication did not fully restore normal force control during fast object manipulation in PD.
    • Task requirements, such as speed, are critical for understanding movement deficits in Parkinson's disease.