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Related Experiment Videos

Initial and repeat screening for Chlamydia trachomatis during pregnancy

A D Allaire1, J F Huddleston, W L Graves

  • 1Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill 27599-7570, USA.

Infectious Diseases in Obstetrics and Gynecology
|October 24, 1998
PubMed
Summary
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Chlamydia trachomatis is common in pregnant women, with many positive repeat tests. Risk factors like young age and lower education highlight the need for rescreening during pregnancy.

Area of Science:

  • Reproductive Health
  • Infectious Diseases
  • Public Health

Background:

  • Chlamydia trachomatis (C. trachomatis) is a common sexually transmitted infection.
  • Screening for C. trachomatis is crucial in high-risk populations, including pregnant women.
  • Understanding risk factors for persistent or repeat infections is vital for effective management.

Purpose of the Study:

  • To determine the prevalence of C. trachomatis in pregnant women seeking early prenatal care.
  • To identify risk factors associated with initial positive C. trachomatis tests.
  • To identify risk factors for positive repeat C. trachomatis tests after an initial negative result.

Main Methods:

  • Retrospective cohort study of 2,484 women receiving prenatal care before 20 weeks gestation.

Related Experiment Videos

  • Cervical C. trachomatis testing was performed.
  • Adjusted odds ratios (OR) were calculated for risk factors of initial and repeat positive tests.

    • Main Results:

    • The overall prevalence of C. trachomatis was 14.8%, with 10.4% testing positive initially.
    • Women with a positive initial test had a 32.0% rate of positive repeat tests, compared to 5.7% for those with a negative initial test.
    • Risk factors for positive initial tests included younger age, black race/ethnicity, being unmarried, and lower education. Risk factors for positive repeat tests after a negative initial test included younger age, black or white race/ethnicity, and lower education.

    Conclusions:

    • A significant proportion of pregnant women in this inner-city population had C. trachomatis.
    • Specific demographic and educational factors are associated with increased risk of infection.
    • These findings support the need for rescreening for C. trachomatis in the second half of pregnancy for at-risk women.