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Laser-Doppler-flowmetry in preterm newborns during apneic events
G Sabatino1, F Chiarelli, B Angelozzi
1Department of Pediatrics-Neonatal Intensive Care Unit, G. D'Annunzia University, Chieti, Italy.
Panminerva Medica
|October 24, 1998
Summary
Skin blood flow perfusion (SBFP) decreases during apnea in preterm newborns. This reduction is more pronounced in older infants, suggesting age-related physiological changes influence apnea response.
Area of Science:
- Neonatal physiology
- Cardiovascular research
- Perinatal medicine
Background:
- Apneic events are common in preterm infants, potentially impacting skin blood flow.
- Understanding the physiological response to apnea is crucial for neonatal care.
Purpose of the Study:
- To investigate changes in Skin Blood Flow Perfusion (SBFP) during apneic events in preterm newborns.
- To compare SBFP responses between early and later postnatal periods.
Main Methods:
- Laser-Doppler-Flowmetry (LDF) was used to measure SBFP in 15 preterm newborns.
- Eighty-four apneic episodes were analyzed and categorized into two age groups (up to 5 days vs. 5-10 days).
Main Results:
- A statistically significant difference in SBFP reduction was observed between the two age groups.
- Newborns older than five days showed a remarkable increase in mean SBFP reduction during apnea.
- Differences were also noted in hematocrit and the timing of blood flow decrease.
Conclusions:
- Age-related rheological factors (hematocrit, red cell deformability) and cold vasoparalysis may influence apnea response.
- Laser-Doppler-Flowmetry can help identify when newborns can better manage apnea effects by centralizing circulation.