Giant sigmoid diverticulum: a rare manifestation of diverticular disease

We report two unusual cases of giant sigmoid diverticulum, which is a rare manifestation of diverticular disease. Giant diverticula are 3 to 4 cm or greater in size and are produced by gradual enlargement of an acquired pseudodiverticulum that has had superimposed infection, abscess formation, and healing. For more than 3 years, we have observed and managed the first case conservatively, without surgery. The second case represents the largest recorded giant sigmoid diverticulum (33 cm) in the literature. We review the pathogenesis, clinical features, differential diagnosis, and management of this condition.