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Evolving views of protein glycosylation
1Dept of Biochemistry, University of Oxford, UK. kd@glycob.ox.ac.uk
Trends in Biochemical Sciences
|October 27, 1998
Abstract:
The composition, biosynthesis and known roles of oligosaccharides that are attached to glycoproteins suggest that multiple forces have driven the evolution of proteins that create and recognize these structures. The evolution of glycoprotein biosynthesis and recognition mechanisms can be best understood as a sequential development of functions associated with oligosaccharides.