Related Experiment Video

Updated: Jul 23, 2026

Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus
11:28

Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus

Published on: October 7, 2011

The chemokine kidnapping receptor of HHV8

O M Howard, W L Farrar

    The Journal of Clinical Investigation
    |October 28, 1998
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production08:32

    Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

    Published on: March 2, 2014

    A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 406:56

    A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4

    Published on: March 10, 2018

    Related Concept Videos

    Receptor-mediated Endocytosis01:20

    Receptor-mediated Endocytosis

    Receptor-mediated endocytosis is when bulk amounts of specific molecules are imported into a cell after binding to cell surface receptors. The molecules bound to these receptors are taken into the cell through inward folding of the cell surface membrane, which is eventually pinched off into a vesicle within the cell. Structural proteins, such as clathrin, coat the budding vesicle.
    Clathrin-Mediated Endocytosis of LDL
    One well-characterized example of receptor-mediated endocytosis is the...
    Receptor Downregulation in MVBs01:15

    Receptor Downregulation in MVBs

    Multivesicular bodies (MVBs) are mature endosomes that sort ubiquitinated proteins and then fuse with lysosomes to degrade the sorted proteins. Epidermal growth factor (EGF) and its receptor (EGFR) form a complex that can be internalized through endocytosis, sorted into an MVB, and later degraded.
    The EGFR can initiate signaling pathways that  lead to cell proliferation, migration, and differentiation. Overexpression of EGFR  stimulates cells to proliferate. Excessive  EGFR activation may...