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Mapplet: a CORBA-based genome map viewer

K Jungfer1, P Rodriguez-Tomé

  • 1EMBL Outstation-Hinxton, The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

Bioinformatics (Oxford, England)
|October 28, 1998
PubMed
Summary
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This study introduces a unified approach to viewing genetic maps using the Common Object Request Broker Architecture (CORBA). A new CORBA map viewer provides efficient access and visualization of large-scale genetic and physical maps.

Area of Science:

  • Bioinformatics
  • Genomics
  • Computational Biology

Background:

  • Numerous genetic and physical maps are distributed across various sites with disparate access methods.
  • The Common Object Request Broker Architecture (CORBA) presents an opportunity to standardize map viewing.
  • Infobiogen and EBI collaborated to propose a common Interface Definition Language (IDL) for genetic maps.

Purpose of the Study:

  • To develop and demonstrate a unified map viewing system using CORBA.
  • To prove the feasibility of a common IDL for diverse genetic map data.
  • To enhance accessibility and visualization of large-scale genomic maps.

Main Methods:

  • Implementation of a CORBA-based map viewer.
  • Utilization of a proposed common IDL for map data integration.

Related Experiment Videos

  • Integration with the EBI Radiation Hybrid Database.

    • Main Results:

    • A functional CORBA map viewer was developed as a proof of concept.
    • The viewer successfully handles large maps with up to 1000 markers.
    • Demonstrated efficient side-by-side comparison of multiple large maps.
    • Visualized marker density and highlighted different marker types.

    Conclusions:

    • The CORBA map viewer effectively demonstrates the utility of the proposed IDL.
    • Standardized interfaces through CORBA can unify access to distributed genetic map resources.
    • This approach enhances the usability and analytical capabilities for genomic map data.