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[Selenium in health and disease]

A D Inglot1, K Krukowska, E Piasecki

  • 1Laboratorium Wirusologii, Instytutu Immunologii i Terapii Doświadczalnej PAN, Wrocławiu.

Postepy Higieny I Medycyny Doswiadczalnej
|October 28, 1998
PubMed
Summary

Selenium deficiency, prevalent globally and in Poland, causes health issues like Keshan disease. Supplementation with selenocysteine, a biologically active form of selenium, is crucial for preventing disease and mitigating viral pathogenicity.

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Area of Science:

  • Biochemistry
  • Human Nutrition
  • Pathology

Context:

  • Selenium deficiency is a global health concern, affecting numerous regions including Poland.
  • This deficiency is linked to various human body dysfunctions and diseases, most notably Keshan disease.
  • Biologically active selenium, primarily incorporated as selenocysteine, plays a vital role in human health.

Purpose:

  • To highlight the significance of selenium in human health and disease prevention.
  • To emphasize the role of selenocysteine in nutritional supplementation.
  • To underscore the link between selenium levels and viral pathogenicity.

Summary:

  • Selenium deficiency is widespread, leading to health problems such as Keshan disease.
  • Selenocysteine is the most nutritionally beneficial form of selenium for supplementation.
  • Adequate selenium levels are important for reducing the severity of certain viral infections.

Impact:

  • Increased awareness of selenium's importance in public health and disease prevention.
  • Potential for improved nutritional strategies to combat selenium-related disorders.
  • Insights into the interaction between host nutrition and viral disease progression.

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