Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Ulcer + ulcer]

D N Stocker1, A D Christ, R Speich

  • 1Departement Innere Medizin, Universitätsspital Zürich.

Therapeutische Umschau. Revue Therapeutique
|October 28, 1998
PubMed
Summary

An elderly woman experienced a bleeding duodenal ulcer after mistakenly applying a diclofenac plaster to a leg wound. This highlights potential adverse effects from incorrect use of topical medications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reliability of parameters during stair ascent measured with Leonardo Mechanograph(®) Stair A in healthy subjects.

Journal of musculoskeletal & neuronal interactions·2015
Same author

A novel and selective sodium-glucose cotransporter-2 inhibitor, tofogliflozin, improves glycaemic control and lowers body weight in patients with type 2 diabetes mellitus.

Diabetes, obesity & metabolism·2015
Same author

[Quality of life in pulmonal arterial hypertension and in chronic thromboembolic pulmonary hypertension].

Deutsche medizinische Wochenschrift (1946)·2014
Same author

[Supportive therapy in pulmonary arterial hypertension].

Deutsche medizinische Wochenschrift (1946)·2014
Same author

[Imatinib for pulmonary arterial hypertension].

Deutsche medizinische Wochenschrift (1946)·2014
Same author

[Supervised exercise training in patients with pulmonary arterial hypertension - analyses of the effectiveness and safety].

Praxis·2012

Area of Science:

  • Gastroenterology
  • Pharmacology
  • Dermatology

Background:

  • Elderly patient with a history of gastrointestinal ulcers presented with acute bleeding.
  • No significant risk factors were identified besides age and ulcer history.

Observation:

  • Patient inadvertently applied a diclofenac hydroxyethylpyrrolidine patch, prescribed for back pain, to a large leg ulcer (ulcus cruris).
  • Clinical examination confirmed the misapplication of the topical formulation.

Findings:

  • The patient's diclofenac serum concentration was 80 mu/l, indicating a therapeutic level.
  • This level suggests systemic absorption occurred due to the incorrect application site.

Implications:

  • Highlights the risk of inadvertent systemic side-effects from topical medications due to application errors.
  • Emphasizes the need for clear patient counseling on the correct use of novel pharmaceutical formulations.
  • Underscores the importance of considering medication application errors in differential diagnoses for unexplained symptoms.

Related Experiment Videos