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The hypothesis of an ambient level of acetylcholine in the central nervous system
1Département de pathologie, Faculté de médecine, Université de Montréal, Québec, Canada.
Journal of Physiology, Paris
|October 28, 1998
Abstract:
Recent ultrastructural data demonstrate the largely asynaptic character of the cholinergic innervation in many regions of adult rat brain. These data favour the hypothesis of a diffuse transmission/modulation by acetylcholine in the CNS and, by way of consequence, that of a persistent, low level of acetylcholine in the extracellular space.