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[Lymphocyte stimulation of healthy probands with a "Hodgkin's HL-A type" (author's transl)]
Reported correlations between HL-A type and Hodgkin's disease suggest that genetic factors as HL-A associated immune response genes may play a role in the pathogenesis of Hodgkin's disease. Assuming that healthy individuals having a Hodgkin HL-A constellation may demonstrate impaired immune function mitogen stimulation and mixed lymphocyte reaction were carried out. However, lymphocytes of 12 persons with a Hodgkin-HL-A type did not show any abnormality in the in vitro tests when compared to a control group.
Reported correlations between HL-A type and Hodgkin's disease suggest that genetic factors as HL-A associated immune response genes may play a role in the pathogenesis of Hodgkin's disease. Assuming that healthy individuals having a Hodgkin HL-A constellation may demonstrate impaired immune function mitogen stimulation and mixed lymphocyte reaction were carried out. However, lymphocytes of 12 persons with a Hodgkin-HL-A type did not show any abnormality in the in vitro tests when compared to a control group.