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[Autonomic disorders in polyneuropathies]

M J Hilz1, M Dütsch, B Neundörfer

  • 1Neurologische Klinik der Universität Erlangen-Nürnberg. max.hilz@neuro.med.uni-erlangen.de

Medizinische Klinik (Munich, Germany : 1983)
|October 29, 1998
PubMed
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Diabetic neuropathy, a common condition, often presents with autonomic disturbances affecting various bodily functions. This review details these symptoms and explores autonomic dysfunction in other neuropathies.

Area of Science:

  • Neurology
  • Autonomic Nervous System Research

Context:

  • Polyneuropathies frequently involve autonomic disturbances.
  • Diabetic neuropathy is the most common neuropathy globally and serves as a key model for autonomic dysfunction.
  • Autonomic symptoms significantly impact patient quality of life.

Purpose:

  • To review the spectrum of autonomic disturbances associated with diabetic neuropathy.
  • To discuss autonomic symptoms in various other neuropathic conditions.
  • To provide a comprehensive overview of autonomic dysfunction in neuropathies.

Summary:

  • Diabetic neuropathy commonly manifests with autonomic symptoms including pupillary, cardiovascular (e.g., orthostatic hypotension), thermoregulatory, gastrointestinal, and urogenital dysfunction.
  • Unawareness of hypoglycemia is a critical autonomic symptom in diabetic neuropathy.

Related Experiment Videos

  • Autonomic dysfunction is also detailed in alcoholic, Guillain-Barré, paraneoplastic, toxic, and other neuropathies like amyloidosis, porphyria, and HIV-associated neuropathy.

    • Impact:

    • Highlights the broad clinical impact of autonomic disturbances in diabetic and other neuropathies.
    • Emphasizes the need for recognizing and managing autonomic symptoms in neuropathic patients.
    • Serves as a reference for clinicians and researchers on autonomic dysfunction across diverse polyneuropathies.