Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Portal-hypertensive gastropathy

A Toyonaga1, T Iwao

  • 1Department of Medicine II, Kurume University School of Medicine, Japan.

Journal of Gastroenterology and Hepatology
|October 30, 1998
PubMed
Summary

Portal-hypertensive gastropathy (PHG) involves vascular changes in the stomach lining, potentially causing non-variceal bleeding. Treatments like propranolol and shunts may help prevent bleeding from this condition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diurnal decline in the photosynthetic capacity of uppermost leaves in an eggplant canopy grown in a horticultural greenhouse.

Photosynthetica·2024
Same author

Validation of claims data to identify death among aged persons utilizing enrollment data from health insurance unions.

Environmental health and preventive medicine·2019
Same author

Clinicopathological study of superficial-type invasive carcinoma of the colorectum.

International journal of oncology·2011
Same author

Local recurrence of colorectal tumors after endoscopic mucosal resection.

International journal of oncology·2011
Same author

Pneumomediastinum is a frequent but minor complication during esophageal endoscopic submucosal dissection.

Endoscopy·2009
Same author

Visceral fat accumulation is a significant risk factor for white matter lesions in Japanese type 2 diabetic patients.

European journal of clinical investigation·2009

Area of Science:

  • Gastroenterology
  • Hepatology
  • Pathology

Background:

  • Portal-hypertensive gastropathy (PHG) is a condition characterized by vascular changes in the stomach lining.
  • It presents as mucosal and submucosal vascular dilatation without inflammation and can cause non-variceal bleeding.

Purpose of the Study:

  • To provide updated information on the clinical features, pathogenesis, and treatment of portal-hypertensive gastropathy.
  • To clarify the role of portal pressure and humoral factors in PHG development.

Main Methods:

  • Review of clinical features and existing literature on portal-hypertensive gastropathy.
  • Discussion of pathogenetic mechanisms including gastric mucosal haemodynamics.
  • Overview of current and potential treatment strategies.

Main Results:

  • PHG prevalence varies widely; portal pressure and humoral factors are implicated in its pathogenesis.
  • Gastric acid secretion is reduced, and the mucosal barrier is impaired in PHG.
  • Severe PHG can lead to bleeding, while mild cases have little clinical significance. Endoscopic variceal obliteration may worsen PHG in some patients.

Conclusions:

  • Portal-hypertensive gastropathy is a significant cause of non-variceal bleeding in portal hypertension.
  • Pharmacological, surgical, and radiological interventions show promise in preventing PHG-related bleeding.

Related Experiment Videos