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[Treatment-resistant dermatomycoses]

T Matsuda1, T Matsumoto

  • 1Department of Dermatology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

Nihon Ishinkin Gakkai Zasshi = Japanese Journal of Medical Mycology
|October 31, 1998
PubMed
Summary
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Dermatomycoses, common fungal skin infections, often respond to antifungal treatments. However, some cases show resistance due to host factors and fungal virulence, necessitating further investigation.

Area of Science:

  • Mycology
  • Dermatology
  • Infectious Diseases

Context:

  • Dermatomycoses represent a prevalent group of fungal infections impacting the skin and subcutaneous tissues.
  • Current topical and systemic antifungal therapies yield positive clinical and mycological outcomes for most superficial fungal infections.

Purpose:

  • To explore the factors contributing to treatment resistance in specific dermatomycoses cases.
  • To provide a detailed discussion on host-related conditions and fungal virulence as key elements in treatment failure.

Summary:

  • While advancements in antifungal chemotherapy have improved outcomes, certain dermatomycoses remain refractory to standard treatment protocols.
  • The study examines underlying host conditions and fungal virulence as significant contributors to treatment resistance in fungal skin infections.

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Impact:

  • Highlights the need for understanding complex factors beyond basic antifungal efficacy.
  • Informs clinical practice and future research directions for managing challenging dermatomycoses cases.