[Mucocutaneous fungal infection in AIDS patients]

Human immunodeficiency virus (HIV) infection is unique among the cutaneous fungal infections caused by defects of the cell-mediated immune system. A complex interplay exists in the host between fungal virulence factors favoring disease, and immune and non-immune host mechanisms defending against disease. Cell-mediated immunity appears of paramount importance in defense against histoplasmosis, cryptococcosis, mucocutaneous candidiasis, and dermatophytosis. Mucocutaneous candidiasis is especially common in patients with HIV infection. Anti-fungal medicines were effective against candidiasis. However, anti-fungal medicine-resistant candida has been observed. Anti-fungal ointment was effective against dermatophytosis and seborrheic dermatitis. No cases of cutaneous fungal infection resistant to anti-fungal medicine have been observed.